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Gene: Tcf7 (transcription factor 7, T cell specific) Mus musculus
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Symbol: Tcf7
Name: transcription factor 7, T cell specific
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including T cell differentiation; canonical Wnt signaling pathway involved in negative regulation of apoptotic process; and embryonic morphogenesis. Localizes to the nuclear euchromatin. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human TCF7 (transcription factor 7).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI465550; T cell factor-1; T-cell factor 1; T-cell-specific transcription factor 1; TCF-1; TCF-7; Tcf1; transcription factor 7; transcription factor 7, T-cell specific
Orthologs:
Homo sapiens (human) : TCF7 (transcription factor 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tcf7 (transcription factor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcf7 (transcription factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : TCF7 (transcription factor 7)
Canis lupus familiaris (dog) : TCF7 (transcription factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcf7 (transcription factor 7)
Sus scrofa (pig) : TCF7 (transcription factor 7 (T-cell specific, HMG-box))
Chlorocebus sabaeus (green monkey) : TCF7 (transcription factor 7)
Heterocephalus glaber (naked mole-rat) : Tcf7 (transcription factor 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1152,252,371 - 52,283,331 (-)Ensembl
GRCm381152,246,527 - 52,283,383 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371152,066,106 - 52,096,073 (-)NCBIGRCm37mm9NCBIm37
MGSCv361152,096,027 - 52,125,994 (-)NCBImm8
Celera1156,821,774 - 56,852,195 (-)NCBICelera
Cytogenetic Map11 B1.3NCBI
cM Map1131.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Tcf7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314198
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.