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Gene: Kat2b (K(lysine) acetyltransferase 2B) Mus musculus
Symbol: Kat2b
Name: K(lysine) acetyltransferase 2B
Description: Exhibits several functions, including N-acetyltransferase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and transcription coactivator activity. Involved in histone H3-K9 acetylation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter. Localizes to several cellular components, including the Ada2/Gcn5/Ada3 transcription activator complex; actomyosin; and sarcomere. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; liver; and lung. Orthologous to human KAT2B (lysine acetyltransferase 2B); PARTICIPATES IN cortisol signaling pathway; histone modification pathway; p53 signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930006P13Rik; AI461839; AW536563; histone acetylase PCAF; histone acetyltransferase KAT2B; histone acetyltransferase PCAF; lysine acetyltransferase 2B; p/CAF; p300/CBP-associated factor; Pcaf; spermidine acetyltransferase KAT2B
Homo sapiens (human) : KAT2B (lysine acetyltransferase 2B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kat2b (lysine acetyltransferase 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kat2b (lysine acetyltransferase 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : KAT2B (lysine acetyltransferase 2B)
Canis lupus familiaris (dog) : KAT2B (lysine acetyltransferase 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kat2b (lysine acetyltransferase 2B)
Sus scrofa (pig) : KAT2B (lysine acetyltransferase 2B)
Chlorocebus sabaeus (green monkey) : KAT2B (lysine acetyltransferase 2B)
Heterocephalus glaber (naked mole-rat) : Kat2b (lysine acetyltransferase 2B)
more info ...
Related Pseudogenes: Kat2b-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1753,566,861 - 53,672,720 (+)Ensembl
GRCm381753,566,774 - 53,672,721 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371753,706,640 - 53,812,045 (+)NCBIGRCm37mm9NCBIm37
MGSCv361753,032,244 - 53,137,649 (+)NCBImm8
Celera1757,012,177 - 57,114,622 (+)NCBICelera
Cytogenetic Map17 CNCBI
cM Map1727.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kat2b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314210
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.