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Gene: Kat2b (K(lysine) acetyltransferase 2B) Mus musculus
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Symbol: Kat2b
Name: K(lysine) acetyltransferase 2B
Description: Exhibits several functions, including N-acetyltransferase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and transcription coactivator activity. Involved in histone H3-K9 acetylation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter. Localizes to several cellular components, including the Ada2/Gcn5/Ada3 transcription activator complex; actomyosin; and sarcomere. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; liver; and lung. Orthologous to human KAT2B (lysine acetyltransferase 2B); PARTICIPATES IN cortisol signaling pathway; histone modification pathway; p53 signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930006P13Rik; AI461839; AW536563; histone acetylase PCAF; histone acetyltransferase KAT2B; histone acetyltransferase PCAF; lysine acetyltransferase 2B; p/CAF; p300/CBP-associated factor; Pcaf; spermidine acetyltransferase KAT2B
Orthologs:
Homo sapiens (human) : KAT2B (lysine acetyltransferase 2B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kat2b (lysine acetyltransferase 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kat2b (lysine acetyltransferase 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : KAT2B (lysine acetyltransferase 2B)
Canis lupus familiaris (dog) : KAT2B (lysine acetyltransferase 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kat2b (lysine acetyltransferase 2B)
Sus scrofa (pig) : KAT2B (lysine acetyltransferase 2B)
Chlorocebus sabaeus (green monkey) : KAT2B (lysine acetyltransferase 2B)
Heterocephalus glaber (naked mole-rat) : Kat2b (lysine acetyltransferase 2B)
more info ...
Related Pseudogenes: Kat2b-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1753,566,861 - 53,672,720 (+)Ensembl
GRCm381753,566,774 - 53,672,721 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371753,706,640 - 53,812,045 (+)NCBIGRCm37mm9NCBIm37
MGSCv361753,032,244 - 53,137,649 (+)NCBImm8
Celera1757,012,177 - 57,114,622 (+)NCBICelera
Cytogenetic Map17 CNCBI
cM Map1727.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kat2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314210
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.