Tdrd6 (tudor domain containing 6) - Chinchilla Research Resource Database
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Gene: Tdrd6 (tudor domain containing 6) Mus musculus
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Symbol: Tdrd6
Name: tudor domain containing 6
CRRD ID: 1314294
Description: Involved in germ cell development; spermatogenesis; and spliceosomal snRNP assembly. Localizes to cytoplasmic ribonucleoprotein granule; endoplasmic reticulum; and ribonucleoprotein complex. Is expressed in spermatid; spermatocyte; and testis. Orthologous to human TDRD6 (tudor domain containing 6); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AB097085; NY-CO-45-like; Tdr2; tudor domain-containing protein 6; tudor repeat 2 protein
Orthologs:
Homo sapiens (human) : TDRD6 (tudor domain containing 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tdrd6 (tudor domain containing 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tdrd6 (tudor domain containing 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TDRD6 (tudor domain containing 6)
Canis lupus familiaris (dog) : TDRD6 (tudor domain containing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tdrd6 (tudor domain containing 6)
Sus scrofa (pig) : TDRD6 (tudor domain containing 6)
Chlorocebus sabaeus (African green monkey) : TDRD6 (tudor domain containing 6)
Heterocephalus glaber (naked mole-rat) : Tdrd6 (tudor domain containing 6)
more info ...
Related Pseudogenes: Gm18337  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,926,225 - 43,942,737 (-)NCBI
GRCm381743,615,334 - 43,631,846 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,615,335 - 43,630,299 (-)EnsemblGRCm38mm10GRCm38
MGSCv371743,752,284 - 43,767,248 (-)NCBIGRCm37mm9NCBIm37
MGSCv361743,078,390 - 43,093,354 (-)NCBImm8
Celera1747,040,264 - 47,053,379 (-)NCBICelera
Cytogenetic Map17B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:12477932   PMID:16093322   PMID:17141210   PMID:17662146   PMID:19345099   PMID:19584108   PMID:21267068   PMID:21383078   PMID:21670278   PMID:25762440   PMID:27149095   PMID:28254886  
PMID:28263986   PMID:28378742   PMID:28444146   PMID:29459677   PMID:32325033  


Genomics

Comparative Map Data
Tdrd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,926,225 - 43,942,737 (-)NCBI
GRCm381743,615,334 - 43,631,846 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,615,335 - 43,630,299 (-)EnsemblGRCm38mm10GRCm38
MGSCv371743,752,284 - 43,767,248 (-)NCBIGRCm37mm9NCBIm37
MGSCv361743,078,390 - 43,093,354 (-)NCBImm8
Celera1747,040,264 - 47,053,379 (-)NCBICelera
Cytogenetic Map17B3NCBI
TDRD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl646,687,875 - 46,704,319 (+)EnsemblGRCh38hg38GRCh38
GRCh38646,680,268 - 46,704,319 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37646,655,612 - 46,672,056 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,763,825 - 46,778,109 (+)NCBINCBI36hg18NCBI36
Celera648,208,136 - 48,224,578 (+)NCBI
Cytogenetic Map6p12.3NCBI
HuRef646,378,891 - 46,395,328 (+)NCBIHuRef
CHM1_1646,659,038 - 46,675,469 (+)NCBICHM1_1
Tdrd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0919,917,613 - 19,932,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,917,603 - 19,932,920 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,795,343 - 18,810,350 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,039,971 - 13,055,118 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1913,036,819 - 13,051,943 (+)NCBI
Celera915,067,715 - 15,082,864 (+)NCBICelera
Cytogenetic Map9q13NCBI
Tdrd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,517,930 - 11,531,869 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,517,094 - 11,531,816 (+)NCBIChiLan1.0ChiLan1.0
TDRD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1647,542,367 - 47,556,964 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0646,265,074 - 46,287,015 (+)NCBIMhudiblu_PPA_v0panPan3
TDRD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1214,849,278 - 14,863,290 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11214,850,019 - 14,863,588 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tdrd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647613,646,678 - 13,660,891 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TDRD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl741,468,780 - 41,483,637 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1741,468,589 - 41,485,146 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,129,241 - 48,145,813 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TDRD6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1725,573,730 - 25,587,052 (-)Ensembl
ChlSab1.11725,573,189 - 25,588,368 (-)NCBI
Tdrd6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475413,943,651 - 13,958,322 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
CRRD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171795643651959238Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171819938152202007Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171820316552205351Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171883413352834133Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172536594043665344Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172618203852604676Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172749681845311728Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172750432261504322Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172831148062311728Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined172982162963821740Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3072257564722705Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3076892947728778Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173290000053800000Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173495684169858931Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173565926669659396Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173648271570482715Mouse
1301474Hcbip2_mhexachlorobenzene induced porphyria 2 (mouse)Not determined173748216445311728Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173840588672405969Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173849862572498625Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173849862572498625Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4022744774227623Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174063218774632187Mouse
1302069Bbaa8_mB.burgdorferi-associated arthritis 8 (mouse)Not determined174274029443665344Mouse
4141478Hbnr7_mHeligmosomoides bakeri nematode resistance 7 (mouse)Not determined4274029451432094Mouse
25394539Skmw85_mskeletal muscle weight 85, gastroc (mouse)174339677746521031Mouse
26884386Skwq13_mskull length QTL 13, 16 week (mouse)174340000052800000Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174340000067500000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:441
Count of miRNA genes:181
Interacting mature miRNAs:214
Transcripts:ENSMUST00000045717, ENSMUST00000162232, ENSMUST00000168073
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000045717   ⟹   ENSMUSP00000035338
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1743,615,801 - 43,630,266 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162232
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1743,615,559 - 43,620,485 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168073   ⟹   ENSMUSP00000131277
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1743,615,335 - 43,630,299 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233077   ⟹   ENSMUSP00000156656
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1743,615,801 - 43,630,266 (-)Ensembl
RefSeq Acc Id: NM_001161366   ⟹   NP_001154838
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,926,226 - 43,941,190 (-)NCBI
GRCm381743,615,335 - 43,630,299 (-)NCBI
MGSCv371743,752,284 - 43,767,248 (-)RGD
Celera1747,040,263 - 47,053,379 (-)NCBI
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001161367   ⟹   NP_001154839
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,926,226 - 43,941,190 (-)NCBI
GRCm381743,615,335 - 43,630,299 (-)NCBI
MGSCv371743,752,284 - 43,767,248 (-)RGD
Celera1747,040,263 - 47,053,379 (-)NCBI
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001357985   ⟹   NP_001344914
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,926,226 - 43,941,190 (-)NCBI
GRCm381743,615,335 - 43,630,299 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198418   ⟹   NP_940810
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,926,226 - 43,941,190 (-)NCBI
GRCm381743,615,335 - 43,630,299 (-)NCBI
MGSCv371743,752,284 - 43,767,248 (-)RGD
Celera1747,040,263 - 47,053,379 (-)NCBI
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523967   ⟹   XP_006524030
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,926,225 - 43,942,737 (-)NCBI
GRCm381743,615,334 - 43,631,846 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006523968   ⟹   XP_006524031
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,926,225 - 43,942,737 (-)NCBI
GRCm381743,615,334 - 43,631,846 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246343   ⟹   XP_011244645
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,926,225 - 43,942,737 (-)NCBI
GRCm381743,615,334 - 43,631,846 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_940810   ⟸   NM_198418
- Peptide Label: isoform 2
- UniProtKB: P61407 (UniProtKB/Swiss-Prot),   F2Z429 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001154838   ⟸   NM_001161366
- Peptide Label: isoform 1
- UniProtKB: E9PZ50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001154839   ⟸   NM_001161367
- Peptide Label: isoform 3
- UniProtKB: B7ZNI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006524030   ⟸   XM_006523967
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006524031   ⟸   XM_006523968
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011244645   ⟸   XM_011246343
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001344914   ⟸   NM_001357985
- Peptide Label: isoform 4
RefSeq Acc Id: ENSMUSP00000035338   ⟸   ENSMUST00000045717
RefSeq Acc Id: ENSMUSP00000156656   ⟸   ENSMUST00000233077
RefSeq Acc Id: ENSMUSP00000131277   ⟸   ENSMUST00000168073
Protein Domains
Tudor

Promoters
RGD ID:13676120
Promoter ID:EPDNEW_M22209
Type:initiation region
Name:Tdrd6_1
Description:Mus musculus tudor domain containing 6 , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381743,630,299 - 43,630,359EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2679727 AgrOrtholog
Ensembl Genes ENSMUSG00000040140 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000035338 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000131277 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000156656 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000045717 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000168073 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000233077 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro SNase_OB-fold_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tudor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:210510 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2679727 ENTREZGENE
NCBI Gene 210510 ENTREZGENE
Pfam TUDOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tdrd6 PhenoGen
PROSITE TUDOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TUDOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.329058 ENTREZGENE
UniProt A0A3B2W3Z0_MOUSE UniProtKB/TrEMBL
  B2RRD1_MOUSE UniProtKB/TrEMBL
  B7ZNI0 ENTREZGENE, UniProtKB/TrEMBL
  E9PZ50 ENTREZGENE, UniProtKB/TrEMBL
  F2Z429 ENTREZGENE, UniProtKB/TrEMBL
  P61407 ENTREZGENE, UniProtKB/Swiss-Prot