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Gene: Klf16 (Kruppel-like factor 16) Mus musculus
Symbol: Klf16
Name: Kruppel-like factor 16
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in dopamine receptor signaling pathway and negative regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Is expressed in several structures, including brain; embryo mesenchyme; genitourinary system; gut; and retina. Orthologous to human KLF16 (Kruppel like factor 16); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI843742; basic transcription element-binding protein 4; BTE-binding protein 4; BTEB4; dopamine receptor regulating factor; dopamine receptor-regulating factor; DRRF; Krueppel-like factor 16; transcription factor BTEB4
Homo sapiens (human) : KLF16 (Kruppel like factor 16)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Klf16 (Kruppel-like factor 16)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf16 (Kruppel like factor 16)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF16 (Kruppel like factor 16)
Canis lupus familiaris (dog) : KLF16 (Kruppel like factor 16)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf16 (Kruppel like factor 16)
Sus scrofa (pig) : KLF16 (Kruppel like factor 16)
Chlorocebus sabaeus (African green monkey) : KLF16 (Kruppel like factor 16)
Heterocephalus glaber (naked mole-rat) : Klf16 (Kruppel like factor 16)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1080,567,124 - 80,577,321 (-)Ensembl
GRCm381080,567,121 - 80,577,296 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,029,866 - 80,040,041 (-)NCBIGRCm37mm9NCBIm37
MGSCv361079,970,264 - 79,980,423 (-)NCBImm8
Celera1081,584,920 - 81,595,095 (-)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Klf16
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314309
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.