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Gene: Nodal (nodal) Mus musculus
Symbol: Nodal
Name: nodal
CRRD ID: 1314355
Description: Exhibits receptor ligand activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and regulation of transcription by RNA polymerase II. Localizes to extracellular region. Is expressed in several structures, including compacted morula; egg cylinder; embryo mesoderm; inner cell mass; and primitive streak. Human ortholog(s) of this gene implicated in visceral heterotaxy. Orthologous to human NODAL (nodal growth differentiation factor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: early embryo mesoderm formation; Tg.413d; transgenic lethal 413.d
Homo sapiens (human) : NODAL (nodal growth differentiation factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nodal (nodal growth differentiation factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nodal (nodal growth differentiation factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NODAL (nodal growth differentiation factor)
Canis lupus familiaris (dog) : NODAL (nodal growth differentiation factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nodal (nodal growth differentiation factor)
Sus scrofa (pig) : NODAL (nodal growth differentiation factor)
Chlorocebus sabaeus (African green monkey) : NODAL (nodal growth differentiation factor)
Heterocephalus glaber (naked mole-rat) : Nodal (nodal growth differentiation factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391061,253,751 - 61,261,117 (+)NCBI
GRCm381061,417,972 - 61,425,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1061,417,972 - 61,425,338 (+)EnsemblGRCm38mm10GRCm38
MGSCv371060,880,720 - 60,888,085 (+)NCBIGRCm37mm9NCBIm37
MGSCv361060,813,657 - 60,819,993 (+)NCBImm8
Celera1062,519,279 - 62,526,659 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nodal
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314355
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.