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Gene: CUL7 (cullin 7) Homo sapiens
Symbol: CUL7
Name: cullin 7
Description: The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3M1; CUL-7; cullin-7; dJ20C7.5; KIAA0076
Mus musculus (house mouse) : Cul7 (cullin 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cul7 (cullin 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul7 (cullin 7)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL7 (cullin 7)
Canis lupus familiaris (dog) : CUL7 (cullin 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul7 (cullin 7)
Sus scrofa (pig) : CUL7 (cullin 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38643,037,617 - 43,053,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37643,005,355 - 43,021,683 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,113,333 - 43,129,632 (-)NCBINCBI36hg18NCBI36
Build 34643,113,333 - 43,129,632NCBI
Celera644,557,598 - 44,573,926 (-)NCBI
Cytogenetic Map6p21.1NCBI
HuRef642,722,458 - 42,738,676 (-)NCBIHuRef
CHM1_1643,007,804 - 43,024,128 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CUL7
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314380
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.