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Gene: NEIL1 (nei like DNA glycosylase 1) Homo sapiens
Symbol: NEIL1
Name: nei like DNA glycosylase 1
Description: Exhibits hydrolase activity, acting on glycosyl bonds and protein C-terminus binding activity. Involved in base-excision repair; negative regulation of nuclease activity; and response to oxidative stress. Localizes to the cytoplasm and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA endonuclease eight-like glycosylase 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; endonuclease 8-like 1; endonuclease VIII; endonuclease VIII-like 1; FLJ22402; FPG1; hFPG1; NEH1; nei endonuclease VIII-like 1; nei homolog 1; nei-like DNA glycosylase 1; nei-like protein 1; NEI1
Mus musculus (house mouse) : Neil1 (nei endonuclease VIII-like 1 (E. coli))  MGI  Alliance
Rattus norvegicus (Norway rat) : Neil1 (nei-like DNA glycosylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Neil1 (nei like DNA glycosylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NEIL1 (nei like DNA glycosylase 1)
Canis lupus familiaris (dog) : NEIL1 (nei like DNA glycosylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Neil1 (nei like DNA glycosylase 1)
Sus scrofa (pig) : NEIL1 (nei like DNA glycosylase 1)
Chlorocebus sabaeus (green monkey) : NEIL1 (nei like DNA glycosylase 1)
Heterocephalus glaber (naked mole-rat) : Neil1 (nei like DNA glycosylase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1575,346,955 - 75,357,115 (+)Ensembl
GRCh381575,346,638 - 75,357,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371575,639,331 - 75,647,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361573,426,463 - 73,434,641 (+)NCBINCBI36hg18NCBI36
Build 341573,426,462 - 73,434,639NCBI
Celera1552,565,769 - 52,574,027 (+)NCBI
Cytogenetic Map15q24.2NCBI
HuRef1552,397,780 - 52,405,946 (+)NCBIHuRef
CHM1_11575,757,932 - 75,766,193 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NEIL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314485
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.