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Gene: RNF6 (ring finger protein 6) Homo sapiens
Symbol: RNF6
Name: ring finger protein 6
Description: Exhibits androgen receptor binding activity and ubiquitin-protein transferase activity. Involved in positive regulation of transcription, DNA-templated; protein polyubiquitination; and regulation of androgen receptor signaling pathway. Localizes to the cytoplasm and nuclear membrane. Implicated in esophageal cancer and squamous cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686P0776; E3 ubiquitin-protein ligase RNF6; ring finger protein (C3H2C3 type) 6; RING-H2 protein RNF-6; RING-type E3 ubiquitin transferase RNF6
Mus musculus (house mouse) : Rnf6 (ring finger protein (C3H2C3 type) 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf6 (ring finger protein 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf6 (ring finger protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF6 (ring finger protein 6)
Canis lupus familiaris (dog) : RNF6 (ring finger protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf6 (ring finger protein 6)
Sus scrofa (pig) : RNF6 (ring finger protein 6)
more info ...
Related Pseudogenes: RLIMP1   RNF6P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381326,132,115 - 26,223,085 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371326,786,894 - 26,796,686 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361325,684,905 - 25,694,508 (-)NCBINCBI36hg18NCBI36
Build 341325,604,252 - 25,694,508NCBI
Celera137,855,135 - 7,864,738 (-)NCBI
Cytogenetic Map13q12.13NCBI
HuRef137,604,511 - 7,614,114 (-)NCBIHuRef
CHM1_11326,674,379 - 26,764,534 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RNF6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314509
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.