Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: HACE1 (HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1) Homo sapiens
Analyze
Symbol: HACE1
Name: HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
Description: Exhibits Rab GTPase binding activity; Rac GTPase binding activity; and ubiquitin-protein transferase activity. Involved in several processes, including Golgi organization; cellular protein metabolic process; and membrane fusion. Localizes to the Golgi membrane; endoplasmic reticulum; and nuclear body.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E3 ubiquitin-protein ligase HACE1; HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1; HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1; HECT-type E3 ubiquitin transferase HACE1; SPPRS
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386104,728,094 - 104,859,919 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376105,175,968 - 105,307,794 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366105,282,661 - 105,414,487 (-)NCBINCBI36hg18NCBI36
Celera6105,798,434 - 105,930,284 (-)NCBI
Cytogenetic Map6q16.3NCBI
HuRef6102,619,748 - 102,751,184 (-)NCBIHuRef
CHM1_16105,437,913 - 105,569,648 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HACE1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314539
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-13
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.