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Gene: PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha) Homo sapiens
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Symbol: PIP5K1A
Name: phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
Description: Exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity and kinase binding activity. Involved in several processes, including activation of GTPase activity; focal adhesion assembly; and ruffle assembly. Localizes to several cellular components, including the lamellipodium; nuclear speck; and ruffle membrane. Colocalizes with the mRNA cleavage and polyadenylation specificity factor complex; PARTICIPATES IN Arf family mediated signaling pathway; E-cadherin signaling pathway; phosphoinositide metabolic pathway; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; 5-azacytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha; phosphatidylinositol 4-phosphate 5-kinase type I alpha; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha; PIP5K1-alpha; PIP5KIalpha; ptdIns(4)P-5-kinase 1 alpha
Orthologs:
Related Pseudogenes: PIP5K1P1   PIP5K1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,197,954 - 151,249,536 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371151,171,021 - 151,222,007 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,437,696 - 149,488,629 (+)NCBINCBI36hg18NCBI36
Build 341147,984,144 - 148,035,078NCBI
Celera1124,286,312 - 124,337,297 (+)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1122,549,129 - 122,599,938 (+)NCBIHuRef
CHM1_11152,566,349 - 152,617,334 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PIP5K1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314561
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.