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Gene: EVPL (envoplakin) Homo sapiens
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Symbol: EVPL
Name: envoplakin
Description: Exhibits cadherin binding activity. Involved in keratinocyte differentiation and peptide cross-linking. Localizes to the cornified envelope; cytosol; and intermediate filament cytoskeleton. Predicted to colocalize with the intermediate filament.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 210 kDa cornified envelope precursor protein; 210 kDa paraneoplastic pemphigus antigen; EVPK; p210
Orthologs:
Mus musculus (house mouse) : Evpl (envoplakin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Evpl (envoplakin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Evpl (envoplakin)
Pan paniscus (bonobo/pygmy chimpanzee) : EVPL (envoplakin)
Canis lupus familiaris (dog) : EVPL (envoplakin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Evpl (envoplakin)
Sus scrofa (pig) : EVPL (envoplakin)
Chlorocebus sabaeus (African green monkey) : EVPL (envoplakin)
Heterocephalus glaber (naked mole-rat) : Evpl (envoplakin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1776,004,502 - 76,027,452 (-)Ensembl
GRCh381776,006,845 - 76,027,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371774,002,926 - 74,023,533 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,514,522 - 71,535,102 (-)NCBINCBI36hg18NCBI36
Build 341771,514,521 - 71,534,972NCBI
Celera1770,592,970 - 70,613,552 (-)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1769,428,533 - 69,449,119 (-)NCBIHuRef
CHM1_11774,067,719 - 74,088,327 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EVPL
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314586
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.