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Gene: DENND2A (DENN domain containing 2A) Homo sapiens
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Symbol: DENND2A
Name: DENN domain containing 2A
Description: Exhibits Rab guanyl-nucleotide exchange factor activity. Involved in retrograde transport, endosome to Golgi. Localizes to the actin cytoskeleton; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DENN domain-containing protein 2A; DENN/MADD domain containing 2A; FAM31D; KIAA1277
Orthologs:
Mus musculus (house mouse) : Dennd2a (DENN/MADD domain containing 2A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dennd2a (DENN domain containing 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dennd2a (DENN domain containing 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : DENND2A (DENN domain containing 2A)
Canis lupus familiaris (dog) : DENND2A (DENN domain containing 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dennd2a (DENN domain containing 2A)
Sus scrofa (pig) : DENND2A (DENN domain containing 2A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387140,518,418 - 140,641,460 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377140,218,220 - 140,341,285 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367139,864,689 - 139,948,811 (-)NCBINCBI36hg18NCBI36
Celera7134,940,274 - 135,024,392 (-)NCBI
Cytogenetic Map7q34NCBI
HuRef7134,513,715 - 134,597,998 (-)NCBIHuRef
CHM1_17140,152,469 - 140,275,433 (-)NCBICHM1_1
CRA_TCAGchr7v27139,556,410 - 139,640,521 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DENND2A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314588
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.