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Gene: EIF4G1 (eukaryotic translation initiation factor 4 gamma 1) Homo sapiens
Symbol: EIF4G1
Name: eukaryotic translation initiation factor 4 gamma 1
CRRD ID: 1314591
Description: Exhibits several functions, including ATP binding activity; RNA binding activity; and eukaryotic initiation factor 4E binding activity. Involved in several processes, including energy homeostasis; positive regulation of eukaryotic translation initiation factor 4F complex assembly; and regulation of cellular protein metabolic process. Localizes to several cellular components, including cytosol; eukaryotic translation initiation factor 4F complex; and polysome. Implicated in late onset Parkinson's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686A1451; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; EIF4-gamma; EIF4F; EIF4G; EIF4GI; eucaryotic translation initiation factor 4G; eukaryotic translation initiation factor 4 gamma, 1; P220; PARK18
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl3184,314,495 - 184,335,358 (+)EnsemblGRCh38hg38GRCh38
GRCh383184,314,606 - 184,335,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373184,032,283 - 184,053,146 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,515,050 - 185,535,840 (+)NCBINCBI36hg18NCBI36
Celera3182,472,966 - 182,494,042 (+)NCBI
Cytogenetic Map3q27.1NCBI
HuRef3181,439,248 - 181,459,772 (+)NCBIHuRef
CHM1_13183,996,741 - 184,017,602 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on EIF4G1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314591
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.