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Gene: EIF4G1 (eukaryotic translation initiation factor 4 gamma 1) Homo sapiens
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Symbol: EIF4G1
Name: eukaryotic translation initiation factor 4 gamma 1
Description: Exhibits several functions, including ATP binding activity; RNA binding activity; and eukaryotic initiation factor 4E binding activity. Involved in several processes, including energy homeostasis; positive regulation of eukaryotic translation initiation factor 4F complex assembly; and regulation of cellular protein metabolic process. Localizes to several cellular components, including the cytosol; eukaryotic translation initiation factor 4F complex; and polysome. Implicated in late onset Parkinson's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686A1451; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; EIF4-gamma; EIF4F; EIF4G; EIF4GI; eucaryotic translation initiation factor 4G; eukaryotic translation initiation factor 4 gamma, 1; P220; PARK18
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,314,495 - 184,335,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373184,032,283 - 184,053,146 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,515,050 - 185,535,840 (+)NCBINCBI36hg18NCBI36
Celera3182,472,966 - 182,494,042 (+)NCBI
Cytogenetic Map3q27.1NCBI
HuRef3181,439,248 - 181,459,772 (+)NCBIHuRef
CHM1_13183,996,741 - 184,017,602 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on EIF4G1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314591
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.