Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: EXOSC8 (exosome component 8) Homo sapiens
Analyze
Symbol: EXOSC8
Name: exosome component 8
Description: Exhibits identical protein binding activity and mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in RNA metabolic process. Localizes to the cytosol; exosome (RNase complex); and nuclear lumen. Implicated in pontocerebellar hypoplasia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA421P11.3; CBP-interacting protein 3; CIP3; EAP2; exosome complex component RRP43; exosome complex exonuclease RRP43; OIP-2; OIP2; Opa interacting protein 2; opa-interacting protein 2; p9; PCH1C; ribosomal RNA-processing protein 43; RP11-421P11.3; RRP43; Rrp43p
Orthologs:
Mus musculus (house mouse) : Exosc8 (exosome component 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Exosc8 (exosome component 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exosc8 (exosome component 8)
Pan paniscus (bonobo/pygmy chimpanzee) : EXOSC8 (exosome component 8)
Canis lupus familiaris (dog) : EXOSC8 (exosome component 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Exosc8 (exosome component 8)
Sus scrofa (pig) : EXOSC8 (exosome component 8)
Chlorocebus sabaeus (African green monkey) : EXOSC8 (exosome component 8)
Heterocephalus glaber (naked mole-rat) : Exosc8 (exosome component 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1336,998,816 - 37,009,614 (+)Ensembl
GRCh381337,000,373 - 37,009,614 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371337,574,678 - 37,583,751 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361336,472,917 - 36,481,538 (+)NCBINCBI36hg18NCBI36
Build 341336,472,916 - 36,481,533NCBI
Celera1318,641,920 - 18,650,994 (+)NCBI
Cytogenetic Map13q13.3NCBI
HuRef1318,386,195 - 18,395,269 (+)NCBIHuRef
CHM1_11337,542,228 - 37,551,301 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EXOSC8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314633
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.