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Gene: FZD7 (frizzled class receptor 7) Homo sapiens
Symbol: FZD7
Name: frizzled class receptor 7
CRRD ID: 1314691
Description: Exhibits several functions, including PDZ domain binding activity; Wnt-activated receptor activity; and Wnt-protein binding activity. Involved in several processes, including Wnt signaling pathway; negative regulation of cell differentiation; and positive regulation of cellular metabolic process. Localizes to intracellular membrane-bounded organelle; plasma membrane; and recycling endosome membrane. Biomarker of nephroblastoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; Frizzled, drosophila, homolog of, 7; frizzled-7; fz-7; FzE3; hFz7
Mus musculus (house mouse) : Fzd7 (frizzled class receptor 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fzd7 (frizzled class receptor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fzd7 (frizzled class receptor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : FZD7 (frizzled class receptor 7)
Canis lupus familiaris (dog) : FZD7 (frizzled class receptor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fzd7 (frizzled class receptor 7)
Sus scrofa (pig) : FZD7 (frizzled class receptor 7)
Chlorocebus sabaeus (African green monkey) : FZD7 (frizzled class receptor 7)
Heterocephalus glaber (naked mole-rat) : Fzd7 (frizzled class receptor 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2202,034,587 - 202,038,445 (+)EnsemblGRCh38hg38GRCh38
GRCh382202,033,855 - 202,038,441 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372202,899,310 - 202,903,160 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362202,607,555 - 202,611,405 (+)NCBINCBI36hg18NCBI36
Build 342202,724,815 - 202,728,666NCBI
Celera2196,651,081 - 196,654,931 (+)NCBI
Cytogenetic Map2q33.1NCBI
HuRef2194,748,666 - 194,752,510 (+)NCBIHuRef
CHM1_12202,905,837 - 202,909,687 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FZD7
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314691
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.