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Gene: Pak6 (p21 (RAC1) activated kinase 6) Mus musculus
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Symbol: Pak6
Name: p21 (RAC1) activated kinase 6
Description: Predicted to have protein serine/threonine kinase activity. Involved in learning; locomotory behavior; and memory. Predicted to localize to the cell junction; cytoplasm; and nuclear lumen. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Is expressed in central nervous system; retina; submandibular gland primordium; and tooth. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4732456M09; p21 protein (Cdc42/Rac)-activated kinase 6; p21-activated kinase 6; PAK-6; serine/threonine-protein kinase PAK 6
Orthologs:
Homo sapiens (human) : PAK6 (p21 (RAC1) activated kinase 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pak6 (p21 (RAC1) activated kinase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak6 (p21 (RAC1) activated kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK6 (p21 (RAC1) activated kinase 6)
Canis lupus familiaris (dog) : PAK6 (p21 (RAC1) activated kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101957470 (serine/threonine-protein kinase PAK 6)
Sus scrofa (pig) : PAK6 (p21 (RAC1) activated kinase 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382118,663,045 - 118,698,020 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372118,489,313 - 118,523,756 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,354,744 - 118,388,677 (+)NCBImm8
Celera2119,818,133 - 119,852,648 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Pak6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314704
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.