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Gene: REXO4 (REX4 homolog, 3'-5' exonuclease) Homo sapiens
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Symbol: REXO4
Name: REX4 homolog, 3'-5' exonuclease
Description: Exhibits nuclease activity; single-stranded DNA binding activity; and transcription coactivator activity. Involved in DNA metabolic process and positive regulation of transcription by RNA polymerase II. Localizes to the nuclear speck and nucleolus; INTERACTS WITH butan-1-ol; cadmium dichloride; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: exonuclease XPMC2; hPMC2; prevents mitotic catastrophe 2 protein homolog; REX4; REX4, RNA exonuclease 4 homolog; RNA exonuclease 4; Xenopus prevents mitotic catastrophe 2 homolog; Xenopus prevents mitotic catatrophe 2 homolog; XPMC2; XPMC2 prevents mitotic catastrophe 2 homolog; XPMC2H
Orthologs:
Mus musculus (house mouse) : Rexo4 (REX4, 3'-5' exonuclease)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rexo4 (REX4 homolog, 3'-5' exonuclease)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rexo4 (REX4 homolog, 3'-5' exonuclease)
Pan paniscus (bonobo/pygmy chimpanzee) : REXO4 (REX4 homolog, 3'-5' exonuclease)
Canis lupus familiaris (dog) : REXO4 (REX4 homolog, 3'-5' exonuclease)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rexo4 (REX4 homolog, 3'-5' exonuclease)
Sus scrofa (pig) : REXO4 (REX4 homolog, 3'-5' exonuclease)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389133,406,058 - 133,418,172 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379136,271,182 - 136,283,292 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,261,007 - 135,272,985 (-)NCBINCBI36hg18NCBI36
Build 349133,300,741 - 133,312,718NCBI
Celera9106,821,755 - 106,833,737 (-)NCBI
Cytogenetic Map9q34.2NCBI
HuRef9105,773,009 - 105,785,123 (-)NCBIHuRef
CHM1_19136,421,689 - 136,433,799 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on REXO4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314713
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.