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Gene: VAV2 (vav guanine nucleotide exchange factor 2) Homo sapiens
Symbol: VAV2
Name: vav guanine nucleotide exchange factor 2
Description: Exhibits guanyl-nucleotide exchange factor activity and phosphotyrosine residue binding activity. Involved in regulation of GTPase activity and regulation of cell size. Predicted to localize to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: guanine nucleotide exchange factor VAV2; oncogene VAV2; vav 2 guanine nucleotide exchange factor; vav 2 oncogene; VAV-2
Mus musculus (house mouse) : Vav2 (vav 2 oncogene)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vav2 (vav guanine nucleotide exchange factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vav2 (vav guanine nucleotide exchange factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : VAV2 (vav guanine nucleotide exchange factor 2)
Canis lupus familiaris (dog) : VAV2 (vav guanine nucleotide exchange factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vav2 (vav guanine nucleotide exchange factor 2)
Sus scrofa (pig) : VAV2 (vav guanine nucleotide exchange factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389133,761,894 - 133,992,374 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379136,627,016 - 136,857,496 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,616,837 - 135,847,226 (-)NCBINCBI36hg18NCBI36
Build 349133,656,570 - 133,886,959NCBI
Celera9107,174,789 - 107,404,640 (-)NCBI
Cytogenetic Map9q34.2NCBI
HuRef9106,127,910 - 106,303,677 (-)NCBIHuRef
CHM1_19136,775,446 - 137,005,937 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on VAV2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314818
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.