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Gene: Ash1l (ASH1 like histone lysine methyltransferase) Mus musculus
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Symbol: Ash1l
Name: ASH1 like histone lysine methyltransferase
Description: Exhibits histone methyltransferase activity (H3-K4 specific) and histone methyltransferase activity (H3-K9 specific). Involved in several processes, including negative regulation of intracellular signal transduction; reproductive structure development; and tarsal gland development. Predicted to localize to Golgi apparatus and nucleoplasm. Is expressed in early conceptus; inner cell mass; oocyte; and ureter. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 52. Orthologous to human ASH1L (ASH1 like histone lysine methyltransferase); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8030453L17Rik; absent small and homeotic disks protein 1 homolog; absent, small, or homeotic 1-like; absent, small, or homeotic discs 1; Ash1; ash1 (absent, small, or homeotic)-like; ash1 (absent, small, or homeotic)-like (Drosophila); ASH1-like protein; chromatin remodeling factor; E430018P19Rik; histone-lysine N-methyltransferase ASH1L; Kmt2h; probable histone-lysine N-methyltransferase ASH1L
Orthologs:
Homo sapiens (human) : ASH1L (ASH1 like histone lysine methyltransferase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ash1l (ASH1 like histone lysine methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ash1l (ASH1 like histone lysine methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ASH1L (ASH1 like histone lysine methyltransferase)
Canis lupus familiaris (dog) : ASH1L (ASH1 like histone lysine methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ash1l (ASH1 like histone lysine methyltransferase)
Sus scrofa (pig) : ASH1L (ASH1 like histone lysine methyltransferase)
Chlorocebus sabaeus (African green monkey) : ASH1L (ASH1 like histone lysine methyltransferase)
Heterocephalus glaber (naked mole-rat) : Ash1l (ASH1 like histone lysine methyltransferase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl388,950,622 - 89,079,375 (+)EnsemblGRCm38mm10GRCm38
GRCm38388,950,414 - 89,079,375 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37388,769,734 - 88,883,297 (+)NCBIGRCm37mm9NCBIm37
MGSCv36389,051,739 - 89,165,302 (+)NCBImm8
Celera389,004,378 - 89,118,066 (+)NCBICelera
Cytogenetic Map3F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ash1l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314919
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.