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Gene: DGCR8 (DGCR8 microprocessor complex subunit) Homo sapiens
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Symbol: DGCR8
Name: DGCR8 microprocessor complex subunit
Description: Exhibits RNA binding activity; heme binding activity; and protein homodimerization activity. Contributes to ribonuclease III activity. Involved in primary miRNA processing. Localizes to the cytoplasm and microprocessor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C22orf12; chromosome 22 open reading frame 12; DGCR8, microprocessor complex subunit; DGCRK6; DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8; Gy1; microprocessor complex subunit DGCR8; pasha
Orthologs:
Mus musculus (house mouse) : Dgcr8 (DGCR8, microprocessor complex subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dgcr8 (DGCR8 microprocessor complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dgcr8 (DGCR8 microprocessor complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : DGCR8 (DGCR8 microprocessor complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dgcr8 (DGCR8 microprocessor complex subunit)
Sus scrofa (pig) : DGCR8 (DGCR8 microprocessor complex subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,080,232 - 20,111,877 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372220,067,755 - 20,099,400 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,447,834 - 18,479,400 (+)NCBINCBI36hg18NCBI36
Build 342218,442,387 - 18,473,952NCBI
Celera223,919,807 - 3,951,450 (+)NCBI
Cytogenetic Map22q11.21NCBI
HuRef223,688,418 - 3,720,061 (+)NCBIHuRef
CHM1_12220,067,440 - 20,099,084 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DGCR8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314941
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.