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Gene: Kdm4a (lysine (K)-specific demethylase 4A) Mus musculus
Symbol: Kdm4a
Name: lysine (K)-specific demethylase 4A
CRRD ID: 1314961
Description: Exhibits histone demethylase activity. Involved in cardiac muscle hypertrophy in response to stress and negative regulation of histone H3-K9 trimethylation. Localizes to pericentric heterochromatin. Is expressed in several structures, including branchial arch; central nervous system; dorsal root ganglion; early conceptus; and genitourinary system. Orthologous to human KDM4A (lysine demethylase 4A); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A; D4Ertd222; D4Ertd222e; JHDM3; JHDM3A; jmjC domain-containing histone demethylation protein 3A; Jmjd2; Jmjd2a; jumonji domain containing 2A; jumonji domain-containing protein 2A; lysine-specific demethylase 4A; MGC28562; mKIAA0677
Homo sapiens (human) : KDM4A (lysine demethylase 4A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm4a (lysine demethylase 4A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm4a (lysine demethylase 4A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM4A (lysine demethylase 4A)
Canis lupus familiaris (dog) : KDM4A (lysine demethylase 4A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm4a (lysine demethylase 4A)
Sus scrofa (pig) : KDM4A (lysine demethylase 4A)
Chlorocebus sabaeus (African green monkey) : KDM4A (lysine demethylase 4A)
Heterocephalus glaber (naked mole-rat) : Kdm4a (lysine demethylase 4A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394117,994,154 - 118,037,242 (-)NCBI
GRCm384118,136,957 - 118,180,090 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4118,136,957 - 118,180,043 (-)EnsemblGRCm38mm10GRCm38
MGSCv374117,809,609 - 117,852,648 (-)NCBIGRCm37mm9NCBIm37
MGSCv364117,639,975 - 117,677,878 (-)NCBImm8
Celera4116,859,945 - 116,902,916 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map454.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm4a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314961
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.