Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kdm4a (lysine (K)-specific demethylase 4A) Mus musculus
Analyze
Symbol: Kdm4a
Name: lysine (K)-specific demethylase 4A
CRRD ID: 1314961
Description: Exhibits histone demethylase activity. Involved in cardiac muscle hypertrophy in response to stress and negative regulation of histone H3-K9 trimethylation. Localizes to pericentric heterochromatin. Is expressed in several structures, including branchial arch; central nervous system; dorsal root ganglion; early conceptus; and genitourinary system. Orthologous to human KDM4A (lysine demethylase 4A); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A; D4Ertd222; D4Ertd222e; JHDM3; JHDM3A; jmjC domain-containing histone demethylation protein 3A; Jmjd2; Jmjd2a; jumonji domain containing 2A; jumonji domain-containing protein 2A; lysine-specific demethylase 4A; MGC28562; mKIAA0677
Orthologs:
Homo sapiens (human) : KDM4A (lysine demethylase 4A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm4a (lysine demethylase 4A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm4a (lysine demethylase 4A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM4A (lysine demethylase 4A)
Canis lupus familiaris (dog) : KDM4A (lysine demethylase 4A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm4a (lysine demethylase 4A)
Sus scrofa (pig) : KDM4A (lysine demethylase 4A)
Chlorocebus sabaeus (African green monkey) : KDM4A (lysine demethylase 4A)
Heterocephalus glaber (naked mole-rat) : Kdm4a (lysine demethylase 4A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394117,994,154 - 118,037,242 (-)NCBI
GRCm384118,136,957 - 118,180,090 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4118,136,957 - 118,180,043 (-)EnsemblGRCm38mm10GRCm38
MGSCv374117,809,609 - 117,852,648 (-)NCBIGRCm37mm9NCBIm37
MGSCv364117,639,975 - 117,677,878 (-)NCBImm8
Celera4116,859,945 - 116,902,916 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map454.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kdm4a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314961
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.