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Gene: PDCD1LG2 (programmed cell death 1 ligand 2) Homo sapiens
Symbol: PDCD1LG2
Name: programmed cell death 1 ligand 2
Description: Involved in negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; and negative regulation of interleukin-10 production. Predicted to localize to the external side of plasma membrane; INTERACTS WITH 17beta-estradiol; 5-fluorouracil; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B7 dendritic cell molecule; B7-DC; B7DC; bA574F11.2; Btdc; butyrophilin B7-DC; CD273; MGC142238; MGC142240; PD-1 ligand 2; PD-1-ligand 2; PD-L2; PDCD1 ligand 2; PDCD1L2; PDL2; programmed death ligand 2
Mus musculus (house mouse) : Pdcd1lg2 (programmed cell death 1 ligand 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdcd1lg2 (programmed cell death 1 ligand 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdcd1lg2 (programmed cell death 1 ligand 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PDCD1LG2 (programmed cell death 1 ligand 2)
Canis lupus familiaris (dog) : PDCD1LG2 (programmed cell death 1 ligand 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdcd1lg2 (programmed cell death 1 ligand 2)
Sus scrofa (pig) : PDCD1LG2 (programmed cell death 1 ligand 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3895,510,438 - 5,571,282 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3795,510,512 - 5,571,282 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3695,500,570 - 5,560,398 (+)NCBINCBI36hg18NCBI36
Build 3495,500,569 - 5,560,398NCBI
Celera95,436,182 - 5,496,918 (+)NCBI
Cytogenetic Map9p24.1NCBI
HuRef95,466,254 - 5,526,976 (+)NCBIHuRef
CHM1_195,510,742 - 5,571,459 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PDCD1LG2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1314998
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.