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Gene: RUVBL2 (RuvB like AAA ATPase 2) Homo sapiens
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Symbol: RUVBL2
Name: RuvB like AAA ATPase 2
Description: Exhibits several functions, including DNA binding activity; TBP-class protein binding activity; and beta-catenin binding activity. Contributes to ATPase activity. Involved in several processes, including cellular response to estradiol stimulus; chromatin organization; and negative regulation of estrogen receptor binding activity. Localizes to several cellular components, including R2TP complex; centrosome; and nuclear lumen.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; CGI-46; ECP-51; ECP51; erythrocyte cytosolic protein, 51-KD; INO80 complex subunit J; INO80J; repressing pontin 52; REPTIN; reptin 52; Reptin52; RuvB (E coli homolog)-like 2; ruvB-like 2; RuvB-like AAA ATPase 2; RVB2; TAP54-beta; TBP-interacting protein, 48-KD; TIH2; TIP48; TIP49B; TIP60-associated protein 54-beta
Orthologs:
Mus musculus (house mouse) : Ruvbl2 (RuvB-like protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ruvbl2 (RuvB-like AAA ATPase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ruvbl2 (RuvB like AAA ATPase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RUVBL2 (RuvB like AAA ATPase 2)
Canis lupus familiaris (dog) : RUVBL2 (RuvB like AAA ATPase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ruvbl2 (RuvB like AAA ATPase 2)
Sus scrofa (pig) : RUVBL2 (RuvB like AAA ATPase 2)
Chlorocebus sabaeus (African green monkey) : RUVBL2 (RuvB like AAA ATPase 2)
Heterocephalus glaber (naked mole-rat) : Ruvbl2 (RuvB like AAA ATPase 2)
more info ...
Related Pseudogenes: RUVBL2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1948,993,562 - 49,015,970 (+)EnsemblGRCh38hg38GRCh38
GRCh381948,993,448 - 49,015,995 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371949,496,738 - 49,519,183 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,188,968 - 54,210,994 (+)NCBINCBI36hg18NCBI36
Build 341954,188,967 - 54,210,994NCBI
Celera1946,364,487 - 46,386,389 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1945,873,862 - 45,895,902 (+)NCBIHuRef
CHM1_11949,498,934 - 49,521,476 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RUVBL2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315165
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.