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Gene: Dhcr24 (24-dehydrocholesterol reductase) Mus musculus
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Symbol: Dhcr24
Name: 24-dehydrocholesterol reductase
Description: ENCODES a protein that exhibits delta24(24-1) sterol reductase activity (ortholog); delta24-sterol reductase activity (ortholog); enzyme binding (ortholog); INVOLVED IN amyloid precursor protein catabolic process; cholesterol biosynthetic process; cholesterol metabolic process; PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH abnormal circulating cholesterol level; abnormal mesenteric fat pad morphology; decreased body size; ASSOCIATED WITH Alzheimer's disease (ortholog); autism spectrum disorder (ortholog); Desmosterolosis (ortholog); FOUND IN cytoplasm (ortholog); cytoskeleton (ortholog); cytosol (ortholog); INTERACTS WITH (S)-nicotine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310076D10Rik; 3-beta-hydroxysterol delta-24 reductase; 3-beta-hydroxysterol delta-24-reductase; 5830417J06Rik; delta(24)-sterol reductase; mKIAA0018; seladin-1
Orthologs:
Homo sapiens (human) : DHCR24 (24-dehydrocholesterol reductase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dhcr24 (24-dehydrocholesterol reductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dhcr24 (24-dehydrocholesterol reductase)
Pan paniscus (bonobo/pygmy chimpanzee) : DHCR24 (24-dehydrocholesterol reductase)
Canis lupus familiaris (dog) : DHCR24 (24-dehydrocholesterol reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhcr24 (24-dehydrocholesterol reductase)
Sus scrofa (pig) : DHCR24 (24-dehydrocholesterol reductase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384106,561,038 - 106,589,113 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374106,233,643 - 106,261,718 (+)NCBIGRCm37mm9NCBIm37
MGSCv364106,059,082 - 106,084,718 (+)NCBImm8
Celera4104,921,880 - 104,950,010 (+)NCBICelera
Cytogenetic Map4 C7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dhcr24
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315198
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.