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Gene: EXOSC2 (exosome component 2) Homo sapiens
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Symbol: EXOSC2
Name: exosome component 2
Description: Predicted to have RNA binding activity. Involved in positive regulation of cell growth. Localizes to the cytoplasm and nuclear lumen; INTERACTS WITH 17beta-estradiol; afimoxifene; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: exosome complex component RRP4; exosome complex exonuclease RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; ribosomal RNA-processing protein 4; RRP4; Rrp4p; SHRF
Orthologs:
Mus musculus (house mouse) : Exosc2 (exosome component 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Exosc2 (exosome component 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exosc2 (exosome component 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EXOSC2 (exosome component 2)
Canis lupus familiaris (dog) : EXOSC2 (exosome component 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Exosc2 (exosome component 2)
Sus scrofa (pig) : EXOSC2 (exosome component 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389130,693,760 - 130,704,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379133,569,158 - 133,580,452 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369132,558,998 - 132,570,077 (+)NCBINCBI36hg18NCBI36
Build 349130,598,730 - 130,609,808NCBI
Celera9104,107,689 - 104,118,983 (+)NCBI
Cytogenetic Map9q34.12NCBI
HuRef9103,055,772 - 103,067,067 (+)NCBIHuRef
CHM1_19133,718,180 - 133,729,318 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EXOSC2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315266
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.