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Gene: EXOSC2 (exosome component 2) Homo sapiens
Symbol: EXOSC2
Name: exosome component 2
Description: Predicted to have RNA binding activity. Involved in positive regulation of cell growth. Localizes to the cytoplasm and nuclear lumen; INTERACTS WITH 17beta-estradiol; afimoxifene; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: exosome complex component RRP4; exosome complex exonuclease RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; hRrp4p; p7; ribosomal RNA-processing protein 4; RRP4; Rrp4p; SHRF
Mus musculus (house mouse) : Exosc2 (exosome component 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Exosc2 (exosome component 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exosc2 (exosome component 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EXOSC2 (exosome component 2)
Canis lupus familiaris (dog) : EXOSC2 (exosome component 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Exosc2 (exosome component 2)
Sus scrofa (pig) : EXOSC2 (exosome component 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389130,693,760 - 130,704,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379133,569,158 - 133,580,452 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369132,558,998 - 132,570,077 (+)NCBINCBI36hg18NCBI36
Build 349130,598,730 - 130,609,808NCBI
Celera9104,107,689 - 104,118,983 (+)NCBI
Cytogenetic Map9q34.12NCBI
HuRef9103,055,772 - 103,067,067 (+)NCBIHuRef
CHM1_19133,718,180 - 133,729,318 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on EXOSC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315266
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.