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Gene: CYC1 (cytochrome c1) Homo sapiens
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Symbol: CYC1
Name: cytochrome c1
Description: Predicted to have electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. Predicted to be involved in mitochondrial ATP synthesis coupled proton transport and mitochondrial electron transport, ubiquinol to cytochrome c. Localizes to cytosol; mitochondrion; and nuclear body. Implicated in mitochondrial complex III deficiency nuclear type 6.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: complex III subunit 4; complex III subunit IV; cytochrome b-c1 complex subunit 4; cytochrome c-1; cytochrome c1, heme protein, mitochondrial; MC3DN6; ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; UQCR4
Orthologs:
Mus musculus (house mouse) : Cyc1 (cytochrome c-1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyc1 (cytochrome c-1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102023109 (cytochrome c1, heme protein, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100995886 (cytochrome c1, heme protein, mitochondrial)
Canis lupus familiaris (dog) : CYC1 (cytochrome c1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101954680 (cytochrome c1, heme protein, mitochondrial)
Sus scrofa (pig) : CYC1 (cytochrome c1)
Chlorocebus sabaeus (African green monkey) : LOC103237609 (cytochrome c1, heme protein, mitochondrial)
Heterocephalus glaber (naked mole-rat) : LOC101700825 (cytochrome c1, heme protein, mitochondrial)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8144,095,039 - 144,097,525 (+)EnsemblGRCh38hg38GRCh38
GRCh388144,095,076 - 144,097,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378145,149,960 - 145,152,428 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,221,948 - 145,224,416 (+)NCBINCBI36hg18NCBI36
Build 348145,221,986 - 145,224,415NCBI
Celera8141,487,538 - 141,489,945 (+)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8140,425,864 - 140,428,305 (+)NCBIHuRef
CHM1_18145,190,173 - 145,192,638 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CYC1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315303
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.