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Gene: Trip12 (thyroid hormone receptor interactor 12) Mus musculus
Symbol: Trip12
Name: thyroid hormone receptor interactor 12
CRRD ID: 1315319
Description: Predicted to have thyroid hormone receptor binding activity and ubiquitin protein ligase activity. Involved in regulation of embryonic development. Predicted to localize to nuclear speck. Is expressed in brain and genitourinary system. Human ortholog(s) of this gene implicated in Clark-Baraitser syndrome. Orthologous to human TRIP12 (thyroid hormone receptor interactor 12); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110036I07Rik; 6720416K24Rik; AA410158; E3 ubiquitin-protein ligase TRIP12; gene trap locus 6; Gtl; Gtl6; HECT-type E3 ubiquitin transferase TRIP12; MGC31615; thyroid receptor interactor TRIP12; thyroid receptor-interacting protein 12; TR-interacting protein 12; TRIP-12
Homo sapiens (human) : TRIP12 (thyroid hormone receptor interactor 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Trip12 (thyroid hormone receptor interactor 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trip12 (thyroid hormone receptor interactor 12)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIP12 (thyroid hormone receptor interactor 12)
Canis lupus familiaris (dog) : TRIP12 (thyroid hormone receptor interactor 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trip12 (thyroid hormone receptor interactor 12)
Sus scrofa (pig) : TRIP12 (thyroid hormone receptor interactor 12)
Chlorocebus sabaeus (African green monkey) : TRIP12 (thyroid hormone receptor interactor 12)
Heterocephalus glaber (naked mole-rat) : Trip12 (thyroid hormone receptor interactor 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39184,698,910 - 84,818,285 (-)NCBI
GRCm38184,721,189 - 84,850,004 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl184,721,189 - 84,840,516 (-)EnsemblGRCm38mm10GRCm38
MGSCv37184,717,764 - 84,835,879 (-)NCBIGRCm37mm9NCBIm37
MGSCv36184,600,221 - 84,718,314 (-)NCBImm8
Celera184,781,289 - 84,899,379 (-)NCBICelera
Cytogenetic Map1C5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Trip12
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315319
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.