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Gene: Mta2 (metastasis-associated gene family, member 2) Mus musculus
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Symbol: Mta2
Name: metastasis-associated gene family, member 2
Description: Exhibits histone deacetylase activity; transcription coregulator activity; and transcription regulatory region DNA binding activity. Predicted to contribute to transcription regulatory region sequence-specific DNA binding activity. Involved in DNA methylation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Localizes to the NuRD complex. Used to study systemic lupus erythematosus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and retina. Orthologous to human MTA2 (metastasis associated 1 family member 2); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AW550797; Mata1l1; metastais-associated gene family, member 2; metastasis associated 1-like 1; metastasis-associated 1-like 1; metastasis-associated protein 2; metastasis-associated protein MTA2; mmta2; Mta1l1
Orthologs:
Homo sapiens (human) : MTA2 (metastasis associated 1 family member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mta2 (metastasis associated 1 family, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mta2 (metastasis associated 1 family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MTA2 (metastasis associated 1 family member 2)
Canis lupus familiaris (dog) : MTA2 (metastasis associated 1 family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mta2 (metastasis associated 1 family member 2)
Sus scrofa (pig) : MTA2 (metastasis associated 1 family member 2)
Chlorocebus sabaeus (green monkey) : MTA2 (metastasis associated 1 family member 2)
Heterocephalus glaber (naked mole-rat) : Mta2 (metastasis associated 1 family member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl198,941,875 - 8,952,303 (+)Ensembl
GRCm38198,941,920 - 8,952,300 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37199,016,410 - 9,026,790 (+)NCBIGRCm37mm9NCBIm37
MGSCv36199,008,965 - 9,019,345 (+)NCBImm8
Celera198,702,694 - 8,712,899 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mta2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315536
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.