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Gene: DENND5A (DENN domain containing 5A) Homo sapiens
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Symbol: DENND5A
Name: DENN domain containing 5A
Description: Exhibits Rab guanyl-nucleotide exchange factor activity. Involved in retrograde transport, endosome to Golgi. Localizes to the trans-Golgi network. Colocalizes with the retromer complex. Implicated in early infantile epileptic encephalopathy 49.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DENN domain-containing protein 5A; DENN/MADD domain containing 5A; EIEE49; FLJ22354; FLJ33829; FLJ43455; KIAA1091; RAB6 interacting protein 1; rab6-interacting protein 1; RAB6IP1
Orthologs:
Mus musculus (house mouse) : Dennd5a (DENN/MADD domain containing 5A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dennd5a (DENN domain containing 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dennd5a (DENN domain containing 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : DENND5A (DENN domain containing 5A)
Canis lupus familiaris (dog) : DENND5A (DENN domain containing 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dennd5a (DENN domain containing 5A)
Sus scrofa (pig) : DENND5A (DENN domain containing 5A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,138,825 - 9,265,350 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37119,160,372 - 9,286,882 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,116,948 - 9,243,447 (-)NCBINCBI36hg18NCBI36
Build 34119,116,952 - 9,243,447NCBI
Celera119,282,225 - 9,408,081 (-)NCBI
Cytogenetic Map11p15.4NCBI
HuRef118,832,931 - 8,959,599 (-)NCBIHuRef
CHM1_1119,159,270 - 9,285,849 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DENND5A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315561
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.