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Gene: RORB (RAR related orphan receptor B) Homo sapiens
Symbol: RORB
Name: RAR related orphan receptor B
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and melatonin receptor activity. Predicted to be involved in several processes, including cellular response to retinoic acid; neural retina development; and regulation of transcription, DNA-templated. Localizes to the nucleoplasm. Implicated in idiopathic generalized epilepsy 15.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA133M9.1; EIG15; NR1F2; nuclear receptor ROR-beta; nuclear receptor RZR-beta; nuclear receptor subfamily 1 group F member 2; RAR-related orphan receptor B; RAR-related orphan receptor beta; retinoic acid-binding receptor beta; retinoid-related orphan receptor beta; retinoid-related orphan receptor-beta; ROR-BETA; RZR-BETA; RZRB
Mus musculus (house mouse) : Rorb (RAR-related orphan receptor beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rorb (RAR-related orphan receptor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rorb (RAR related orphan receptor B)
Pan paniscus (bonobo/pygmy chimpanzee) : RORB (RAR related orphan receptor B)
Canis lupus familiaris (dog) : RORB (RAR related orphan receptor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rorb (RAR related orphan receptor B)
Sus scrofa (pig) : RORB (RAR related orphan receptor B)
Chlorocebus sabaeus (green monkey) : RORB (RAR related orphan receptor B)
Heterocephalus glaber (naked mole-rat) : Rorb (RAR related orphan receptor B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl974,497,335 - 74,693,177 (+)Ensembl
GRCh38974,497,335 - 74,693,177 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37977,112,252 - 77,303,534 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36976,302,072 - 76,491,937 (+)NCBINCBI36hg18NCBI36
Build 34974,341,852 - 74,531,348NCBI
Celera947,686,322 - 47,876,161 (+)NCBI
Cytogenetic Map9q21.13NCBI
HuRef946,935,089 - 47,124,700 (+)NCBIHuRef
CHM1_1977,258,972 - 77,448,757 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RORB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315588
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.