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Gene: RPA3 (replication protein A3) Homo sapiens
Symbol: RPA3
Name: replication protein A3
Description: Exhibits damaged DNA binding activity and single-stranded DNA binding activity. Involved in DNA repair and DNA replication. Localizes to the DNA replication factor A complex; PARTICIPATES IN DNA replication pathway; homologous recombination pathway of double-strand break repair; mismatch repair pathway; INTERACTS WITH (-)-quinic acid; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: REPA3; replication factor A protein 3; replication protein A 14 kDa subunit; replication protein A3, 14kDa; RF-A protein 3; RP-A p14
Mus musculus (house mouse) : Rpa3 (replication protein A3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rpa3 (replication protein A3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rpa3 (replication protein A3)
Pan paniscus (bonobo/pygmy chimpanzee) : RPA3 (replication protein A3)
Canis lupus familiaris (dog) : RPA3 (replication protein A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rpa3 (replication protein A3)
Sus scrofa (pig) : RPA3 (replication protein A3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3877,636,518 - 7,718,607 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3777,676,347 - 7,758,238 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3677,643,100 - 7,724,763 (-)NCBINCBI36hg18NCBI36
Build 3477,449,816 - 7,531,478NCBI
Celera77,644,982 - 7,725,987 (-)NCBI
Cytogenetic Map7p21.3NCBI
HuRef77,525,171 - 7,607,577 (-)NCBIHuRef
CHM1_177,675,912 - 7,757,838 (-)NCBICHM1_1
CRA_TCAGchr7v277,723,782 - 7,804,410 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RPA3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315635
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.