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Gene: IL18RAP (interleukin 18 receptor accessory protein) Homo sapiens
Symbol: IL18RAP
Name: interleukin 18 receptor accessory protein
Description: Exhibits interleukin-18 receptor activity. Involved in interleukin-18-mediated signaling pathway and positive regulation of NF-kappaB transcription factor activity. Localizes to the interleukin-18 receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: accessory protein-like; ACPL; CD218 antigen-like family member B; CD218b; CDw218b; cluster of differentiation w218b; IL-18 receptor accessory protein; IL-18 receptor beta; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R accessory protein-like; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RB; interleukin-1 receptor 7; interleukin-18 receptor accessory protein; interleukin-18 receptor accessory protein-like; interleukin-18 receptor beta; MGC120589; MGC120590
Mus musculus (house mouse) : Il18rap (interleukin 18 receptor accessory protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il18rap (interleukin 18 receptor accessory protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il18rap (interleukin 18 receptor accessory protein)
Pan paniscus (bonobo/pygmy chimpanzee) : IL18RAP (interleukin 18 receptor accessory protein)
Canis lupus familiaris (dog) : IL18RAP (interleukin 18 receptor accessory protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il18rap (interleukin 18 receptor accessory protein)
Sus scrofa (pig) : IL18RAP (interleukin 18 receptor accessory protein)
Chlorocebus sabaeus (green monkey) : IL18RAP (interleukin 18 receptor accessory protein)
Heterocephalus glaber (naked mole-rat) : Il18rap (interleukin 18 receptor accessory protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2102,418,689 - 102,452,565 (+)Ensembl
GRCh382102,418,550 - 102,452,568 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372103,035,254 - 103,069,025 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,401,686 - 102,435,457 (+)NCBINCBI36hg18NCBI36
Build 342102,493,771 - 102,527,543NCBI
Celera297,236,395 - 97,270,167 (+)NCBI
Cytogenetic Map2q12.1NCBI
HuRef296,799,620 - 96,833,394 (+)NCBIHuRef
CHM1_12103,039,551 - 103,073,326 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IL18RAP
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315691
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.