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Gene: AKR1C1 (aldo-keto reductase family 1 member C1) Homo sapiens
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Symbol: AKR1C1
Name: aldo-keto reductase family 1 member C1
CRRD ID: 1315695
Description: Exhibits bile acid binding activity and oxidoreductase activity. Involved in several processes, including glycoside metabolic process; progesterone metabolic process; and retinal metabolic process. Localizes to cytosol. Biomarker of obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2-ALPHA-HSD; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; aldo-keto reductase C; aldo-keto reductase family 1, member C1; C9; chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase isoform DD1; H-37; HAKRC; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity hepatic bile acid-binding protein; indanol dehydrogenase; MBAB; MGC8954; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type II 3-alpha-hydroxysteroid dehydrogenase
Orthologs:
No known orthologs. homologs ...
Related Pseudogenes: AKR1C7P   AKR1C8P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl104,963,253 - 4,983,283 (+)EnsemblGRCh38hg38GRCh38
GRCh38104,963,415 - 4,983,283 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37105,005,454 - 5,020,158 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36104,995,454 - 5,010,158 (+)NCBINCBI36hg18NCBI36
Build 34104,995,453 - 5,010,157NCBI
Cytogenetic Map10p15.1NCBI
HuRef104,965,234 - 4,979,935 (-)NCBIHuRef
CHM1_1105,005,791 - 5,020,495 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AKR1C1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315695
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.