Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TRAF6 (TNF receptor associated factor 6) Homo sapiens
Symbol: TRAF6
Name: TNF receptor associated factor 6
CRRD ID: 1315706
Description: Exhibits several functions, including enzyme binding activity; tumor necrosis factor receptor binding activity; and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; protein ubiquitination; and regulation of transcription, DNA-templated. Localizes to several cellular components, including nucleus; perinuclear region of cytoplasm; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E3 ubiquitin-protein ligase TRAF6; interleukin-1 signal transducer; MGC:3310; RING finger protein 85; RING-type E3 ubiquitin transferase TRAF6; RNF85; TNF receptor-associated factor 6; TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Mus musculus (house mouse) : Traf6 (TNF receptor-associated factor 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Traf6 (TNF receptor associated factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Traf6 (TNF receptor associated factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAF6 (TNF receptor associated factor 6)
Canis lupus familiaris (dog) : TRAF6 (TNF receptor associated factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Traf6 (TNF receptor associated factor 6)
Sus scrofa (pig) : TRAF6 (TNF receptor associated factor 6)
Chlorocebus sabaeus (African green monkey) : TRAF6 (TNF receptor associated factor 6)
Heterocephalus glaber (naked mole-rat) : Traf6 (TNF receptor associated factor 6)
more info ...
Related Pseudogenes: TRAF6P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1136,483,769 - 36,510,272 (-)EnsemblGRCh38hg38GRCh38
GRCh381136,483,769 - 36,510,313 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371136,505,317 - 36,531,863 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361136,467,302 - 36,488,398 (-)NCBINCBI36hg18NCBI36
Build 341136,467,298 - 36,488,398NCBI
Celera1136,661,891 - 36,684,256 (-)NCBI
Cytogenetic Map11p12NCBI
HuRef1136,207,402 - 36,234,755 (-)NCBIHuRef
CHM1_11136,504,096 - 36,530,410 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TRAF6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315706
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.