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Gene: FBXL5 (F-box and leucine rich repeat protein 5) Homo sapiens
Symbol: FBXL5
Name: F-box and leucine rich repeat protein 5
Description: Exhibits iron ion binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; iron ion homeostasis; and protein ubiquitination. Localizes to the SCF ubiquitin ligase complex and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: F-box and leucine-rich repeat protein 5; F-box protein FBL4/FBL5; F-box protein FBL5; F-box/LRR-repeat protein 5; FBL4; FBL5; FLR1; p45SKP2-like protein
Mus musculus (house mouse) : Fbxl5 (F-box and leucine-rich repeat protein 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxl5 (F-box and leucine-rich repeat protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxl5 (F-box and leucine rich repeat protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXL5 (F-box and leucine rich repeat protein 5)
Canis lupus familiaris (dog) : FBXL5 (F-box and leucine rich repeat protein 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxl5 (F-box and leucine rich repeat protein 5)
Sus scrofa (pig) : FBXL5 (F-box and leucine rich repeat protein 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38415,604,381 - 15,681,544 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37415,606,007 - 15,661,487 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36415,215,252 - 15,266,111 (-)NCBINCBI36hg18NCBI36
Build 34415,282,422 - 15,333,282NCBI
Celera416,069,952 - 16,121,669 (-)NCBI
Cytogenetic Map4p15.32NCBI
HuRef414,956,302 - 15,007,653 (-)NCBIHuRef
CHM1_1415,603,953 - 15,655,030 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FBXL5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315757
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.