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Gene: FBXL5 (F-box and leucine rich repeat protein 5) Homo sapiens
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Symbol: FBXL5
Name: F-box and leucine rich repeat protein 5
Description: Exhibits iron ion binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; iron ion homeostasis; and protein ubiquitination. Localizes to the SCF ubiquitin ligase complex and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: F-box and leucine-rich repeat protein 5; F-box protein FBL4/FBL5; F-box protein FBL5; F-box/LRR-repeat protein 5; FBL4; FBL5; FLR1; p45SKP2-like protein
Orthologs:
Mus musculus (house mouse) : Fbxl5 (F-box and leucine-rich repeat protein 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxl5 (F-box and leucine-rich repeat protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxl5 (F-box and leucine rich repeat protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXL5 (F-box and leucine rich repeat protein 5)
Canis lupus familiaris (dog) : FBXL5 (F-box and leucine rich repeat protein 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxl5 (F-box and leucine rich repeat protein 5)
Sus scrofa (pig) : FBXL5 (F-box and leucine rich repeat protein 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38415,604,381 - 15,681,544 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37415,606,007 - 15,661,487 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36415,215,252 - 15,266,111 (-)NCBINCBI36hg18NCBI36
Build 34415,282,422 - 15,333,282NCBI
Celera416,069,952 - 16,121,669 (-)NCBI
Cytogenetic Map4p15.32NCBI
HuRef414,956,302 - 15,007,653 (-)NCBIHuRef
CHM1_1415,603,953 - 15,655,030 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FBXL5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315757
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.