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Gene: RPF2 (ribosome production factor 2 homolog) Homo sapiens
Symbol: RPF2
Name: ribosome production factor 2 homolog
Description: Exhibits 5S rRNA binding activity. Involved in protein localization to nucleolus; regulation of signal transduction by p53 class mediator; and ribosomal large subunit biogenesis. Localizes to the nucleolus and nucleoplasm; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bA397G5.4; brix domain containing 1; brix domain-containing protein 1; BXDC1; FLJ21087; homolog of Rpf2; ribosomal processing factor 2 homolog; ribosome biogenesis protein RPF2 homolog
Mus musculus (house mouse) : Rpf2 (ribosome production factor 2 homolog)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rpf2 (ribosome production factor 2 homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rpf2 (ribosome production factor 2 homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : RPF2 (ribosome production factor 2 homolog)
Canis lupus familiaris (dog) : RPF2 (ribosome production factor 2 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rpf2 (ribosome production factor 2 homolog)
Sus scrofa (pig) : RPF2 (ribosome production factor 2 homolog)
more info ...
Related Pseudogenes: RPF2P1   RPF2P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6110,982,015 - 111,028,263 (+)Ensembl
GRCh386110,982,017 - 111,028,263 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376111,303,274 - 111,347,299 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366111,409,984 - 111,453,487 (+)NCBINCBI36hg18NCBI36
Celera6112,049,860 - 112,093,367 (+)NCBI
Cytogenetic Map6q21NCBI
HuRef6108,874,129 - 108,917,809 (+)NCBIHuRef
CHM1_16111,566,290 - 111,612,540 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RPF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315787
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.