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Gene: AEBP1 (AE binding protein 1) Homo sapiens
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Symbol: AEBP1
Name: AE binding protein 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and collagen binding activity. Involved in negative regulation of transcription by RNA polymerase II and regulation of collagen fibril organization. Localizes to the collagen-containing extracellular matrix and extracellular exosome. Implicated in Ehlers-Danlos syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACLP; adipocyte enhancer binding protein 1; adipocyte enhancer-binding protein 1; AE-binding protein 1; aortic carboxypeptidase-like protein; FLJ33612
Orthologs:
Mus musculus (house mouse) : Aebp1 (AE binding protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aebp1 (AE binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aebp1 (AE binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AEBP1 (AE binding protein 1)
Canis lupus familiaris (dog) : AEBP1 (AE binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aebp1 (AE binding protein 1)
Sus scrofa (pig) : AEBP1 (AE binding protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,104,320 - 44,114,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37744,143,960 - 44,154,164 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,110,485 - 44,120,684 (+)NCBINCBI36hg18NCBI36
Build 34743,917,199 - 43,927,398NCBI
Celera744,241,911 - 44,252,113 (+)NCBI
Cytogenetic Map7p13NCBI
HuRef744,029,222 - 44,039,430 (+)NCBIHuRef
CHM1_1744,147,805 - 44,158,013 (+)NCBICHM1_1
CRA_TCAGchr7v2744,183,452 - 44,193,659 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on AEBP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315812
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.