Gene: RIPOR2 (RHO family interacting cell polarization regulator 2) Homo sapiens
Symbol: RIPOR2
Name: RHO family interacting cell polarization regulator 2
Description: This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. [provided by RefSeq, Sep 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C6orf32; DFNB104; DIFF40; DIFF48; FAM65B; family with sequence similarity 65 member B; family with sequence similarity 65, member B; hypothetical protein LOC9750; KIAA0386; myogenesis-related and NCAM-associated protein homolog; MYONAP; PL48; rho family-interacting cell polarization regulator 2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38624,804,281 - 25,042,288 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37624,804,512 - 24,936,275 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,947,566 - 24,985,562 (-)NCBINCBI36hg18NCBI36
Build 34624,947,575 - 24,985,562NCBI
Celera626,037,884 - 26,138,491 (-)NCBI
Cytogenetic Map6p22.3NCBI
HuRef624,753,953 - 24,854,449 (-)NCBIHuRef
CHM1_1624,808,614 - 25,044,502 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RIPOR2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315839
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.