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Gene: Insm2 (insulinoma-associated 2) Mus musculus
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Symbol: Insm2
Name: insulinoma-associated 2
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; neuron differentiation; and regulation of cell cycle process. Predicted to localize to nucleus and transcriptional repressor complex. Is expressed in several structures, including adrenal gland; central nervous system; eye; genitourinary system; and pancreas. Orthologous to human INSM2 (INSM transcriptional repressor 2); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: insulinoma-associated protein 2; methylated in liver tumor 1; mlt 1; Mlt1
Orthologs:
Homo sapiens (human) : INSM2 (INSM transcriptional repressor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Insm2 (INSM transcriptional repressor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Insm2 (INSM transcriptional repressor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : INSM2 (INSM transcriptional repressor 2)
Canis lupus familiaris (dog) : INSM2 (INSM transcriptional repressor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Insm2 (INSM transcriptional repressor 2)
Sus scrofa (pig) : INSM2 (INSM transcriptional repressor 2)
Chlorocebus sabaeus (African green monkey) : INSM2 (INSM transcriptional repressor 2)
Heterocephalus glaber (naked mole-rat) : Insm2 (INSM transcriptional repressor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1255,599,427 - 55,602,086 (+)EnsemblGRCm38mm10GRCm38
GRCm381255,598,917 - 55,602,018 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371256,699,904 - 56,703,005 (+)NCBIGRCm37mm9NCBIm37
MGSCv361256,517,603 - 56,519,084 (+)NCBImm8
Celera1256,748,546 - 56,751,647 (+)NCBICelera
Cytogenetic Map12C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Insm2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315854
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.