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Gene: SUV39H2 (suppressor of variegation 3-9 homolog 2) Homo sapiens
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Symbol: SUV39H2
Name: suppressor of variegation 3-9 homolog 2
CRRD ID: 1315884
Description: Exhibits S-adenosyl-L-methionine binding activity; histone methyltransferase activity (H3-K9 specific); and zinc ion binding activity. Involved in cellular response to hypoxia; chromatin organization; and negative regulation of transcription by RNA polymerase II. Localizes to chromatin; PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metabolic pathway; histone modification pathway; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ23414; H3-K9-HMTase 2; histone H3-K9 methyltransferase 2; histone-lysine N-methyltransferase SUV39H2; KMT1B; lysine N-methyltransferase 1B; su(var)3-9 homolog 2
Orthologs:
Mus musculus (house mouse) : Suv39h2 (suppressor of variegation 3-9 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Suv39h2 (suppressor of variegation 3-9 homolog 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Suv39h2 (suppressor of variegation 3-9 homolog 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SUV39H2 (suppressor of variegation 3-9 homolog 2)
Canis lupus familiaris (dog) : SUV39H2 (suppressor of variegation 3-9 homolog 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Suv39h2 (suppressor of variegation 3-9 homolog 2)
Sus scrofa (pig) : SUV39H2 (suppressor of variegation 3-9 homolog 2)
Chlorocebus sabaeus (African green monkey) : SUV39H2 (suppressor of variegation 3-9 homolog 2)
Heterocephalus glaber (naked mole-rat) : Suv39h2 (suppressor of variegation 3-9 homolog 2)
more info ...
Related Pseudogenes: AL713998.2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1014,878,820 - 14,904,315 (+)EnsemblGRCh38hg38GRCh38
GRCh381014,878,866 - 14,904,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371014,920,782 - 14,946,314 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,960,905 - 14,986,320 (+)NCBINCBI36hg18NCBI36
Build 341014,960,904 - 14,986,308NCBI
Celera1014,848,822 - 14,874,354 (+)NCBI
Cytogenetic Map10p13NCBI
HuRef1014,831,341 - 14,856,796 (+)NCBIHuRef
CHM1_11014,921,216 - 14,946,434 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SUV39H2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315884
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.