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Gene: CFL2 (cofilin 2) Homo sapiens
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Symbol: CFL2
Name: cofilin 2
CRRD ID: 1315906
Description: Predicted to have actin filament binding activity. Involved in actin filament depolymerization and positive regulation of actin filament depolymerization. Localizes to Z disc. Implicated in nemaline myopathy 7.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cofilin 2 (muscle); cofilin, muscle isoform; cofilin-2; NEM7; nemaline myopathy type 7
Orthologs:
Mus musculus (house mouse) : Cfl2 (cofilin 2, muscle)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cfl2 (cofilin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfl2 (cofilin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CFL2 (cofilin 2)
Canis lupus familiaris (dog) : CFL2 (cofilin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfl2 (cofilin 2)
Sus scrofa (pig) : CFL2 (cofilin 2)
Chlorocebus sabaeus (African green monkey) : CFL2 (cofilin 2)
Heterocephalus glaber (naked mole-rat) : Cfl2 (cofilin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1434,709,113 - 34,714,823 (-)EnsemblGRCh38hg38GRCh38
GRCh381434,709,113 - 34,714,593 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371435,179,588 - 35,184,029 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,249,343 - 34,253,657 (-)NCBINCBI36hg18NCBI36
Build 341434,249,400 - 34,253,649NCBI
Celera1415,043,756 - 15,048,197 (-)NCBI
Cytogenetic Map14q13.1NCBI
HuRef1415,292,957 - 15,297,397 (-)NCBIHuRef
CHM1_11435,178,338 - 35,182,776 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CFL2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315906
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.