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Gene: Cfl2 (cofilin 2, muscle) Mus musculus
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Symbol: Cfl2
Name: cofilin 2, muscle
CRRD ID: 1315907
Description: Exhibits actin filament binding activity. Involved in actin cytoskeleton organization; muscle cell cellular homeostasis; and skeletal muscle tissue development. Predicted to localize to Z disc and cortical actin cytoskeleton. Is expressed in neural retinal epithelium. Human ortholog(s) of this gene implicated in nemaline myopathy 7. Orthologous to human CFL2 (cofilin 2); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cofilin, muscle isoform; cofilin-2
Orthologs:
Homo sapiens (human) : CFL2 (cofilin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cfl2 (cofilin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfl2 (cofilin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CFL2 (cofilin 2)
Canis lupus familiaris (dog) : CFL2 (cofilin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfl2 (cofilin 2)
Sus scrofa (pig) : CFL2 (cofilin 2)
Chlorocebus sabaeus (African green monkey) : CFL2 (cofilin 2)
Heterocephalus glaber (naked mole-rat) : Cfl2 (cofilin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1254,858,809 - 54,862,877 (-)EnsemblGRCm38mm10GRCm38
GRCm381254,858,815 - 54,862,877 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371255,959,804 - 55,963,864 (-)NCBIGRCm37mm9NCBIm37
MGSCv361255,776,952 - 55,781,012 (-)NCBImm8
Celera1256,156,897 - 56,160,843 (-)NCBICelera
Cytogenetic Map12C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cfl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315907
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.