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Gene: Cfl2 (cofilin 2, muscle) Mus musculus
Symbol: Cfl2
Name: cofilin 2, muscle
CRRD ID: 1315907
Description: Exhibits actin filament binding activity. Involved in actin cytoskeleton organization; muscle cell cellular homeostasis; and skeletal muscle tissue development. Predicted to localize to Z disc and cortical actin cytoskeleton. Is expressed in neural retinal epithelium. Human ortholog(s) of this gene implicated in nemaline myopathy 7. Orthologous to human CFL2 (cofilin 2); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cofilin, muscle isoform; cofilin-2
Homo sapiens (human) : CFL2 (cofilin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cfl2 (cofilin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfl2 (cofilin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CFL2 (cofilin 2)
Canis lupus familiaris (dog) : CFL2 (cofilin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfl2 (cofilin 2)
Sus scrofa (pig) : CFL2 (cofilin 2)
Chlorocebus sabaeus (African green monkey) : CFL2 (cofilin 2)
Heterocephalus glaber (naked mole-rat) : Cfl2 (cofilin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1254,858,809 - 54,862,877 (-)EnsemblGRCm38mm10GRCm38
GRCm381254,858,815 - 54,862,877 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371255,959,804 - 55,963,864 (-)NCBIGRCm37mm9NCBIm37
MGSCv361255,776,952 - 55,781,012 (-)NCBImm8
Celera1256,156,897 - 56,160,843 (-)NCBICelera
Cytogenetic Map12C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cfl2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315907
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.