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Gene: RAD18 (RAD18 E3 ubiquitin protein ligase) Homo sapiens
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Symbol: RAD18
Name: RAD18 E3 ubiquitin protein ligase
Description: Exhibits several functions, including Y-form DNA binding activity; identical protein binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of cell death; positive regulation of chromosome segregation; and protein autoubiquitination. Localizes to the centrosome; chromosome; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; postreplication repair protein RAD18; RAD18 homolog; RAD18, E3 ubiquitin protein ligase; RAD18, S. cerevisiae, homolog; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73
Orthologs:
Mus musculus (house mouse) : Rad18 (RAD18 E3 ubiquitin protein ligase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rad18 (RAD18 E3 ubiquitin protein ligase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rad18 (RAD18 E3 ubiquitin protein ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : RAD18 (RAD18 E3 ubiquitin protein ligase)
Canis lupus familiaris (dog) : RAD18 (RAD18 E3 ubiquitin protein ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rad18 (RAD18 E3 ubiquitin protein ligase)
Sus scrofa (pig) : RAD18 (RAD18 E3 ubiquitin protein ligase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl38,775,402 - 8,963,773 (-)Ensembl
GRCh3838,877,075 - 8,969,249 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3738,918,880 - 9,005,159 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3638,896,560 - 8,980,146 (-)NCBINCBI36hg18NCBI36
Build 3438,896,560 - 8,980,146NCBI
Celera38,853,629 - 8,939,882 (-)NCBI
Cytogenetic Map3p25.3NCBI
HuRef38,853,076 - 8,939,344 (-)NCBIHuRef
CHM1_138,869,168 - 8,955,418 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RAD18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1315923
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.