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Gene: STEAP2 (STEAP2 metalloreductase) Homo sapiens
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Symbol: STEAP2
Name: STEAP2 metalloreductase
Description: Predicted to have cupric reductase activity and ferric-chelate reductase (NADPH) activity. Involved in several processes, including Golgi to plasma membrane transport; endocytosis; and regulated exocytosis. Localizes to several cellular components, including the cytoplasmic vesicle; cytosol; and integral component of Golgi membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IPCA1; metalloreductase STEAP2; PCANAP1; prostate cancer associated protein 1; prostate cancer-associated protein 1; protein up-regulated in metastatic prostate cancer; protein upregulated in metastatic prostate cancer; PUMPCn; six transmembrane epithelial antigen of prostate 2; six transmembrane epithelial antigen of the prostate 2; six-transmembrane epithelial antigen of prostate 2; SixTransMembrane Protein of Prostate 1; STAMP1; STEAP family member 2, metalloreductase; STMP
Orthologs:
Mus musculus (house mouse) : Steap2 (six transmembrane epithelial antigen of prostate 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Steap2 (STEAP2 metalloreductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Steap2 (STEAP2 metalloreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : STEAP2 (STEAP2 metalloreductase)
Canis lupus familiaris (dog) : STEAP2 (STEAP2 metalloreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Steap2 (STEAP2 metalloreductase)
Sus scrofa (pig) : STEAP2 (STEAP2 metalloreductase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38790,211,740 - 90,243,408 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37789,841,000 - 89,866,992 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36789,678,936 - 89,704,928 (+)NCBINCBI36hg18NCBI36
Build 34789,485,650 - 89,511,580NCBI
Celera784,545,103 - 84,571,097 (+)NCBI
Cytogenetic Map7q21.13NCBI
HuRef784,451,093 - 84,477,088 (+)NCBIHuRef
CHM1_1789,770,966 - 89,796,957 (+)NCBICHM1_1
CRA_TCAGchr7v2789,171,774 - 89,197,769 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on STEAP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316015
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.