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Gene: STEAP2 (STEAP2 metalloreductase) Homo sapiens
Symbol: STEAP2
Name: STEAP2 metalloreductase
Description: Predicted to have cupric reductase activity and ferric-chelate reductase (NADPH) activity. Involved in several processes, including Golgi to plasma membrane transport; endocytosis; and regulated exocytosis. Localizes to several cellular components, including the cytoplasmic vesicle; cytosol; and integral component of Golgi membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IPCA1; metalloreductase STEAP2; PCANAP1; prostate cancer associated protein 1; prostate cancer-associated protein 1; protein up-regulated in metastatic prostate cancer; protein upregulated in metastatic prostate cancer; PUMPCn; six transmembrane epithelial antigen of prostate 2; six transmembrane epithelial antigen of the prostate 2; six-transmembrane epithelial antigen of prostate 2; SixTransMembrane Protein of Prostate 1; STAMP1; STEAP family member 2, metalloreductase; STMP
Mus musculus (house mouse) : Steap2 (six transmembrane epithelial antigen of prostate 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Steap2 (STEAP2 metalloreductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Steap2 (STEAP2 metalloreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : STEAP2 (STEAP2 metalloreductase)
Canis lupus familiaris (dog) : STEAP2 (STEAP2 metalloreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Steap2 (STEAP2 metalloreductase)
Sus scrofa (pig) : STEAP2 (STEAP2 metalloreductase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38790,211,740 - 90,243,408 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37789,841,000 - 89,866,992 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36789,678,936 - 89,704,928 (+)NCBINCBI36hg18NCBI36
Build 34789,485,650 - 89,511,580NCBI
Celera784,545,103 - 84,571,097 (+)NCBI
Cytogenetic Map7q21.13NCBI
HuRef784,451,093 - 84,477,088 (+)NCBIHuRef
CHM1_1789,770,966 - 89,796,957 (+)NCBICHM1_1
CRA_TCAGchr7v2789,171,774 - 89,197,769 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on STEAP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316015
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.