Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PPEF2 (protein phosphatase with EF-hand domain 2) Homo sapiens
Symbol: PPEF2
Name: protein phosphatase with EF-hand domain 2
Description: Exhibits Hsp70 protein binding activity; Hsp90 protein binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in negative regulation of MAPK cascade and negative regulation of peptidyl-threonine phosphorylation. Predicted to localize to the cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: PPP7CB; protein phosphatase 7, catalytic subunit, beta isozyme; protein phosphatase with EF hands 2; protein phosphatase, EF hand calcium-binding domain 2; serine/threonine-protein phosphatase with EF-hands 2
Mus musculus (house mouse) : Ppef2 (protein phosphatase, EF hand calcium-binding domain 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppef2 (protein phosphatase with EF-hand domain 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppef2 (protein phosphatase with EF-hand domain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PPEF2 (protein phosphatase with EF-hand domain 2)
Canis lupus familiaris (dog) : PPEF2 (protein phosphatase with EF-hand domain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppef2 (protein phosphatase with EF-hand domain 2)
Sus scrofa (pig) : PPEF2 (protein phosphatase with EF-hand domain 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38475,859,867 - 75,902,452 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37476,781,025 - 76,823,681 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36477,000,049 - 77,042,705 (-)NCBINCBI36hg18NCBI36
Build 34477,138,206 - 77,180,860NCBI
Celera474,081,428 - 74,124,167 (-)NCBI
Cytogenetic Map4q21.1NCBI
HuRef472,533,638 - 72,576,290 (-)NCBIHuRef
CHM1_1476,757,660 - 76,800,341 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPEF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316080
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.