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Gene: PPEF2 (protein phosphatase with EF-hand domain 2) Homo sapiens
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Symbol: PPEF2
Name: protein phosphatase with EF-hand domain 2
Description: Exhibits Hsp70 protein binding activity; Hsp90 protein binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in negative regulation of MAPK cascade and negative regulation of peptidyl-threonine phosphorylation. Predicted to localize to the cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: PPP7CB; protein phosphatase 7, catalytic subunit, beta isozyme; protein phosphatase with EF hands 2; protein phosphatase, EF hand calcium-binding domain 2; serine/threonine-protein phosphatase with EF-hands 2
Orthologs:
Mus musculus (house mouse) : Ppef2 (protein phosphatase, EF hand calcium-binding domain 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppef2 (protein phosphatase with EF-hand domain 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppef2 (protein phosphatase with EF-hand domain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PPEF2 (protein phosphatase with EF-hand domain 2)
Canis lupus familiaris (dog) : PPEF2 (protein phosphatase with EF-hand domain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppef2 (protein phosphatase with EF-hand domain 2)
Sus scrofa (pig) : PPEF2 (protein phosphatase with EF-hand domain 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38475,859,867 - 75,902,452 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37476,781,025 - 76,823,681 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36477,000,049 - 77,042,705 (-)NCBINCBI36hg18NCBI36
Build 34477,138,206 - 77,180,860NCBI
Celera474,081,428 - 74,124,167 (-)NCBI
Cytogenetic Map4q21.1NCBI
HuRef472,533,638 - 72,576,290 (-)NCBIHuRef
CHM1_1476,757,660 - 76,800,341 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PPEF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316080
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.