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Gene: LMO2 (LIM domain only 2) Homo sapiens
Symbol: LMO2
Name: LIM domain only 2
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and E-box binding activity. Involved in cellular response to thyroid hormone stimulus; mRNA transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Localizes to the transcription factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cysteine-rich protein TTG-2; LIM domain only 2 (rhombotin-like 1); LIM domain only protein 2; LMO-2; RBTN2; RBTNL1; RHOM2; rhombotin 2; rhombotin-2; rhombotin-like 1; T-cell translocation gene 2; T-cell translocation protein 2; TTG2
Mus musculus (house mouse) : Lmo2 (LIM domain only 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lmo2 (LIM domain only 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lmo2 (LIM domain only 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LMO2 (LIM domain only 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lmo2 (LIM domain only 2)
Sus scrofa (pig) : LMO2 (LIM domain only 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1133,858,576 - 33,892,076 (-)Ensembl
GRCh381133,858,576 - 33,892,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371133,880,122 - 33,913,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361133,836,698 - 33,870,412 (-)NCBINCBI36hg18NCBI36
Build 341133,836,700 - 33,870,412NCBI
Celera1134,027,627 - 34,061,421 (-)NCBI
Cytogenetic Map11p13NCBI
HuRef1133,576,315 - 33,610,063 (-)NCBIHuRef
CHM1_11133,879,643 - 33,913,368 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LMO2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316093
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.