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Gene: PRPF6 (pre-mRNA processing factor 6) Homo sapiens
Symbol: PRPF6
Name: pre-mRNA processing factor 6
Description: Exhibits several functions, including androgen receptor binding activity; ribonucleoprotein complex binding activity; and transcription coactivator activity. Involved in RNA localization; positive regulation of transcription by RNA polymerase II; and spliceosomal tri-snRNP complex assembly. Localizes to the nucleus. Implicated in retinitis pigmentosa 60.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: androgen receptor N-terminal domain transactivating protein-1; androgen receptor N-terminal domain-transactivating protein 1; ANT-1; ANT1; C20orf14; chromosome 20 open reading frame 14; hPrp6; p102 U5 small nuclear ribonucleoprotein particle-binding protein; pre-mRNA-processing factor 6; Prp6; PRP6 homolog; PRP6 pre-mRNA processing factor 6 homolog; putative mitochondrial outer membrane protein import receptor; RP60; SNRNP102; TOM; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein; U5-102K
Mus musculus (house mouse) : Prpf6 (pre-mRNA splicing factor 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prpf6 (pre-mRNA processing factor 6)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PRPF6 (pre-mRNA processing factor 6)
Canis lupus familiaris (dog) : PRPF6 (pre-mRNA processing factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prpf6 (pre-mRNA processing factor 6)
Sus scrofa (pig) : PRPF6 (pre-mRNA processing factor 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382063,981,132 - 64,033,100 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372062,612,417 - 62,664,453 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362062,082,875 - 62,134,897 (+)NCBINCBI36hg18NCBI36
Build 342062,082,900 - 62,134,895NCBI
Celera2059,299,064 - 59,350,558 (+)NCBI
Cytogenetic Map20q13.33NCBI
HuRef2059,347,184 - 59,398,551 (+)NCBIHuRef
CHM1_12062,513,489 - 62,564,783 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PRPF6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316097
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.