Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70) Homo sapiens
Analyze
Symbol: SNRNP70
Name: small nuclear ribonucleoprotein U1 subunit 70
Description: Exhibits U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Localizes to U1 snRNP; nucleoplasm; and spliceosomal complex. Implicated in disease of mental health and systemic lupus erythematosus. Biomarker of Alzheimer's disease; PARTICIPATES IN spliceosome pathway; INTERACTS WITH 5-aza-2'-deoxycytidine; atrazine; bathocuproine disulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: RNPU1Z; RPU1; small nuclear ribonucleoprotein 70kDa (U1); small nuclear ribonucleoprotein, U1 70kDa subunit; Snp1; SNRP70; U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; U170K; U1AP; U1RNP
Orthologs:
Mus musculus (house mouse) : Snrnp70 (small nuclear ribonucleoprotein 70 (U1))  MGI  Alliance
Rattus norvegicus (Norway rat) : Snrnp70 (small nuclear ribonucleoprotein U1 subunit 70)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snrnp70 (small nuclear ribonucleoprotein U1 subunit 70)
Pan paniscus (bonobo/pygmy chimpanzee) : SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70)
Canis lupus familiaris (dog) : SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snrnp70 (small nuclear ribonucleoprotein U1 subunit 70)
Sus scrofa (pig) : SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70)
Chlorocebus sabaeus (African green monkey) : SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70)
Heterocephalus glaber (naked mole-rat) : Snrnp70 (small nuclear ribonucleoprotein U1 subunit 70)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1949,085,419 - 49,108,605 (+)EnsemblGRCh38hg38GRCh38
GRCh381949,085,451 - 49,108,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371949,588,465 - 49,611,870 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,280,277 - 54,303,682 (+)NCBINCBI36hg18NCBI36
Build 341954,280,276 - 54,303,681NCBI
Celera1946,455,683 - 46,479,094 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1945,964,935 - 45,988,033 (+)NCBIHuRef
CHM1_11949,590,504 - 49,613,985 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SNRNP70
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316126
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.