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Gene: ANTXR1 (ANTXR cell adhesion molecule 1) Homo sapiens
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Symbol: ANTXR1
Name: ANTXR cell adhesion molecule 1
Description: Exhibits actin filament binding activity; collagen binding activity; and transmembrane signaling receptor activity. Involved in actin cytoskeleton reorganization and substrate adhesion-dependent cell spreading. Localizes to the external side of plasma membrane; filopodium membrane; and lamellipodium membrane. Implicated in colorectal carcinoma. Biomarker of breast cancer; colorectal cancer; gallbladder carcinoma; and triple-receptor negative breast cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2310008J16Rik; 2810405N18Rik; anthrax toxin receptor 1; ATR; FLJ10601; FLJ11298; FLJ21776; GAPO; TEM8; tumor endothelial marker 8
Orthologs:
Mus musculus (house mouse) : Antxr1 (anthrax toxin receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Antxr1 (ANTXR cell adhesion molecule 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Antxr1 (ANTXR cell adhesion molecule 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANTXR1 (ANTXR cell adhesion molecule 1)
Canis lupus familiaris (dog) : ANTXR1 (ANTXR cell adhesion molecule 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Antxr1 (ANTXR cell adhesion molecule 1)
Sus scrofa (pig) : ANTXR1 (ANTXR cell adhesion molecule 1)
Chlorocebus sabaeus (African green monkey) : ANTXR1 (ANTXR cell adhesion molecule 1)
Heterocephalus glaber (naked mole-rat) : Antxr1 (ANTXR cell adhesion molecule 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl269,013,178 - 69,249,327 (+)Ensembl
GRCh38269,013,144 - 69,249,327 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37269,240,276 - 69,476,459 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,093,993 - 69,329,806 (+)NCBINCBI36hg18NCBI36
Celera269,091,094 - 69,326,525 (+)NCBI
Cytogenetic Map2p13.3NCBI
HuRef268,976,485 - 69,212,089 (+)NCBIHuRef
CHM1_1269,169,599 - 69,405,781 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ANTXR1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316162
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.