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Gene: Dusp22 (dual specificity phosphatase 22) Mus musculus
Symbol: Dusp22
Name: dual specificity phosphatase 22
CRRD ID: 1316167
Description: Exhibits protein tyrosine kinase binding activity and protein tyrosine phosphatase activity. Involved in several processes, including negative regulation of T cell mediated immunity; regulation of signal transduction; and transforming growth factor beta receptor signaling pathway. Predicted to localize to several cellular components, including cytosol; filamentous actin; and leading edge of lamellipodium. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and somite. Orthologous to human DUSP22 (dual specificity phosphatase 22); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110028K04Rik; AW212235; dual specificity protein phosphatase 22; JK; JKAP; JS; JSP1; LMW-DSP2; low molecular weight dual specificity phosphatase 2; MGC118031; MKPX; RP23-217J3.1
Homo sapiens (human) : DUSP22 (dual specificity phosphatase 22)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dusp22 (dual specificity phosphatase 22)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp22 (dual specificity phosphatase 22)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP22 (dual specificity phosphatase 22)
Canis lupus familiaris (dog) : DUSP22 (dual specificity phosphatase 22)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp22 (dual specificity phosphatase 22)
Sus scrofa (pig) : DUSP22 (dual specificity phosphatase 22)
Chlorocebus sabaeus (African green monkey) : DUSP22 (dual specificity phosphatase 22)
Heterocephalus glaber (naked mole-rat) : Dusp22 (dual specificity phosphatase 22)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391330,844,042 - 30,895,215 (+)NCBI
GRCm381330,660,059 - 30,711,232 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1330,659,999 - 30,711,231 (+)EnsemblGRCm38mm10GRCm38
MGSCv371330,751,965 - 30,803,094 (+)NCBIGRCm37mm9NCBIm37
MGSCv361330,667,561 - 30,718,690 (+)NCBImm8
Celera1330,874,241 - 30,925,414 (+)NCBICelera
Cytogenetic Map13A3.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dusp22
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316167
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.